C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 233/88 (2006.01) A61K 31/4168 (2006.01) A61K 31/4174 (2006.01) A61K 31/4178 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61K 31/4725 (2006.01) A61K 31/497 (2006.01) A61K 31/506 (2006.01) A61K 31/538 (2006.01) A61P 25/16 (2006.01) A61P 25/28 (2006.01) C07D 233/86 (2006.01) C07D 401/04 (2006.01) C07D 401/10 (2006.01) C07D 403/10 (2006.01) C07D 405/04 (2006.01) C07D 405/10 (2006.01) C07D 405/14 (2006.01) C07D 409/10 (2006.01) C07D 413/10 (2006.01) C07D 417/04 (2006.01)
Patent
CA 2630680
This invention relates to novel compounds having the structural formula I below: and to their pharmaceutically acceptable salt, compositions and methods of use. These novel compounds provide a treatment or prophylaxis of cognitive impairment, Alzheimer Disease, neurodegeneration and dementia.
La présente invention concerne de nouveaux composés ayant la formule structurale I ci-dessous : et leurs sels pharmaceutiquement acceptables, des compositions et des procédés d'utilisation. Ces nouveaux composés permettent un traitement ou une prophylaxie de troubles cognitifs, de la maladie d'Alzheimer, de la neurodégénérescence et de la démence.
Berg Stefan
Burrows Jeremy
Chessari Gianni
Congreve Miles Stuart
Hedstrom Johan
Astex Therapeutics Ltd
Astrazeneca Ab
Mccarthy Tetrault Llp
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