C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 207/04 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) A61K 31/55 (2006.01) A61K 51/00 (2006.01) C07D 207/06 (2006.01) C07D 211/14 (2006.01) C07D 211/18 (2006.01) C07D 223/04 (2006.01) C07D 401/06 (2006.01) C07D 409/06 (2006.01) C07D 495/06 (2006.01)
Patent
CA 2177739
Novel 2-arylalkenyl-azacycloalkane derivatives as sigma receptor ligands, having formula (I), wherein Ar is optionally mono- or trisubstituted aryl or heteroaryl, m is 1 or 2, n is 1 to 3, and R is phenyl or C¿3-7? cycloalkyl; and isomers and addition salts thereof. Antipsychotic and gastroenterology drugs are also provided.
Nouveaux dérivés de 2-arylalkényl-azacycloalkanes ligands aux récepteurs sigma, de formule (I), dans laquelle: Ar est aryle ou hétéroaryle optionnellement mono à trisubstitué, m a pour valeur 1 ou 2, n a pour valeur 1 à 3, R est phényle, ou cycloalkyle comprenant de 3 à 7 atomes de carbone, leurs isomères et leurs sels d'addition. Médicaments antipsychotiques et utiles en gastro-entérologie.
Calvet Alain Pierre
Jacobelli Henry
Junien Jean-Louis
Riviere Pierre
Roman Francois Joseph
Institut de Recherche Jouveinal
Robic
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