Novel 2-azetidinone derivatives and their use as cholesterol...

Details Novel 2-azetidinone derivatives and their use as cholesterol... Novel 2-azetidinone derivatives and their use as cholesterol...

C - Chemistry, Metallurgy

07

D

C07D 205/08 (2006.01) A61K 31/397 (2006.01) A61P 3/06 (2006.01)

Patent

CA 2610890

Compounds of formula (I) (wherein variable groups are as defined within) pharmaceutically acceptable salts, solvates, solvates of such salts and prodrugs thereof and their use as cholesterol absorption inhibitors for the treatment of hyperlipidaemia are described. Processes for their manufacture and pharmaceutical compositions containing them are also described.

La présente invention décrit des composés de formule (I) (où les groupements variables sont tels que définis dans la description de l'invention), leurs sels et solvates de qualité pharmaceutique, les solvates desdits sels et les prodrogues de ces substances, ainsi que leur emploi en tant qu'inhibiteurs d'absorption de cholestérol pour le traitement des hyperlipémies. La présente invention décrit en outre des procédés de production desdits composés ainsi que des préparations pharmaceutiques les contenant.

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