Novel 2'-c-methyl and 4'-c-methyl nucleoside derivatives

C - Chemistry – Metallurgy – 07 – H

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Details

C07H 19/11 (2006.01) A61K 31/7068 (2006.01) A61P 31/12 (2006.01)

Patent

CA 2618713

Novel 2'-C-methyl nucleoside 5 '-monophosphate and 4'-C-methyl nucleoside 5'- monophosphate derivatives, stereoisomers, and pharmaceutically acceptable salts or prodrugs thereof, their preparation, and their uses for the treatment of hepatitis C viral infection are described.

La présente invention décrit de nouveaux dérivés de 2'-C-méthyl-nucléosides 5'-monophosphates et de 4'-C-méthyl-nucléosides 5'-monophosphates, leurs stéréoisomères et leurs sels ou promédicaments de qualité pharmaceutique, leur synthèse et leur emploi dans le traitement d'une infection par le virus de l'hépatite C.

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