C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 19/11 (2006.01) A61K 31/7068 (2006.01) A61P 31/12 (2006.01)
Patent
CA 2618713
Novel 2'-C-methyl nucleoside 5 '-monophosphate and 4'-C-methyl nucleoside 5'- monophosphate derivatives, stereoisomers, and pharmaceutically acceptable salts or prodrugs thereof, their preparation, and their uses for the treatment of hepatitis C viral infection are described.
La présente invention décrit de nouveaux dérivés de 2'-C-méthyl-nucléosides 5'-monophosphates et de 4'-C-méthyl-nucléosides 5'-monophosphates, leurs stéréoisomères et leurs sels ou promédicaments de qualité pharmaceutique, leur synthèse et leur emploi dans le traitement d'une infection par le virus de l'hépatite C.
Erion Mark D.
Maccoss Malcolm
Olsen David B.
Reddy K. Raja
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
Metabasis Therapeutics Inc.
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