Novel 3,3-diphenylpropylamines, their use and preparation

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 215/54 (2006.01) A61K 31/135 (2006.01) A61K 31/16 (2006.01) A61K 31/40 (2006.01) A61K 31/445 (2006.01) C07C 217/62 (2006.01) C07C 237/30 (2006.01) C07C 311/37 (2006.01) C07D 207/06 (2006.01) C07D 211/14 (2006.01) C07D 295/096 (2006.01)

Patent

CA 2148827

The invention relates to 3,3-diphenylpropylamines of formula (I), wherein R1 signifies hydrogen or methyl, R2 and R3 independently signify hydrogen, methyl, methoxy, hydroxy, carbamoyl, sulphamoyl or halogen, and X represents a tertiary amino group of formula (II), wherein R4 and R5 signify non-aromatic hydrocarbyl groups, which may be the same or different and which together contain at least three carbon atoms, and wherein R4 and R5 may form a ring together with the amine nitrogen, their salts with physiologically acceptable acids and, when the compounds can be in the form of optical isomers, the racemic mixture and the individual enantiomers. The invention also relates to methods for their preparation, pharmaceutical compositions containing the novel compounds, and the use of the compounds for preparing drugs.

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