Novel 35 kd protein

Details Novel 35 kd protein Novel 35 kd protein

C - Chemistry, Metallurgy

12

N

C12N 15/12 (2006.01) A61K 38/00 (2006.01) C07K 14/435 (2006.01) C07K 14/47 (2006.01) C07K 16/18 (2006.01) C12Q 1/02 (2006.01) C12Q 1/68 (2006.01) G01N 33/15 (2006.01) G01N 33/53 (2006.01)

Patent

CA 2484341

It is intended to provide a protein participating in the regulation of sugar production, a polynucleotide encoding the same, a method of screening a compound participating in the regulation of sugar production and a drug for treating or preventing diabetes which contains the compound participating in the regulation of sugar production. A polynucleotide encoding a protein specifically binding to a substance WF00144 is found out from rat liver cells and thus a protein participating in the regulation of sugar production and a polynucleotide encoding the same are provided. Moreover, a method and a substance relating to a method of treating and preventing diabetes are found out and thus a method of treating diabetes relating to the regulation of sugar production relating to the method of treating and preventing diabetes is provided.

L'invention concerne une protéine participant à la régulation de production de glucides, un polynucléotide codant cette protéine, une méthode de criblage d'un composé participant à la régulation de production de glucides et un médicament de traitement ou de prévention des diabètes, contenant le composé participant à la régulation de production de glucides. L'invention concerne un polynucléotide codant une protéine se liant spécifiquement à une substance WF00144 se trouvant dans les cellules hépatiques du rat, ainsi qu'une protéine participant à la régulation de la production de glucides, et qu'un polypeptide codant cette protéine. En outre, l'invention concerne une méthode et une substance associées à une méthode de traitement et de prévention de diabètes, ainsi qu'une méthode de traitement de diabètes associée à la régulation de la production de glucides associée à la méthode de traitement et de prévention de diabètes.

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