Novel 4- halogenated steroids, preparation method and...

C - Chemistry – Metallurgy – 07 – J

Patent

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C07J 41/00 (2006.01) A61K 31/56 (2006.01)

Patent

CA 2285679

The invention concerns compounds of formula (I) in which X is a halogen atom; D represents the residue of a pentagonal or hexagonal cycle, optionally substituted and optionally unsaturated; R1, R2, R3, R4, Y and n are such as defined in the description. The invention also concerns the preparation method and intermediates thereof, their application as medicine and the pharmaceutical compositions containing them.

L'invention a pour objet les composés de formule (I) dans laquelle X est un atome d'halogène, D représente le reste d'un cycle pentagonal ou hexagonal éventuellement substitué et éventuellement porteur d'insaturation, R1, R2, R3, R4, y et n sont tels que définis dans la description, leur procédé et intermédiaire de préparation, leur application comme médicament et les compositions pharmaceutiques les renfermant.

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