Novel 4-phenylpiperidines for the treatment of pruritic...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 211/30 (2006.01) A61K 31/445 (2006.01) C07D 211/26 (2006.01) C07D 211/28 (2006.01) C07D 211/94 (2006.01)

Patent

CA 2332538

Novel compounds having general formula (1), and pharmaceutically and veterinarily acceptable salts thereof wherein R1, R2, R3, W, Y1, Y2, X, n and y are as defined above and processes for their preparation and intermediate compounds prepared therein. The novel compounds are useful for having utility in the treatment of pruritic dermatoses including allergic dermatitis and atopy in animals and humans.

L'invention concerne de nouveaux composés de la formule générale (I) et leurs sels acceptables du point de vue pharmaceutique et vétérinaire. Dans ladite formule, R<1>, R<2>, R<3>, W, Y<1>, Y<2>, X, n et y sont tels que définis. L'invention concerne également des procédés de préparation desdits composés et des composés intermédiaires ainsi préparés. Ces nouveaux composés conviennent pour le traitement de dermatoses prurigineuses, y compris l'eczéma allergique et l'atopie chez l'homme et l'animal.

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