C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 211/76 (2006.01) A61K 31/445 (2006.01) C07D 401/04 (2006.01) C07D 403/04 (2006.01)
Patent
CA 2172377
Compounds of formula (I), wherein J, B, L, X m and M have any of the meanings given in the specifica- tion, their N-oxides, and their pharmaceutically accept- able salts are nonpeptide antagonists of neurokinin A and useful for the treatment of asthma, etc. Also disclosed are pharmaceutical compositions, processes for prepar- ing the compounds of formula (I) and intermediates.
Des composés de la formule (I) dans laquelle J, B, L, X, m et M ont les notations données dans la description de l'invention, leurs oxydes azotés ainsi que leurs sels pharmacologiquement acceptables sont des antagonistes non peptidiques de la neurokinine A, et sont utiles dans le traitement de l'asthme, etc. L'invention se rapporte également aux compositions pharmaceutiques, aux procédés de préparation des composés de formule (I) ainsi qu'à leurs intermédiaires.
Astrazeneca Uk Limited
Smart & Biggar
LandOfFree
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