Novel 4-substituted azetidinones as precursors to...

Details Novel 4-substituted azetidinones as precursors to... Novel 4-substituted azetidinones as precursors to...

C - Chemistry, Metallurgy

07

F

C07F 7/10 (2006.01) C07D 205/08 (2006.01) C07D 477/04 (2006.01) C07D 487/04 (2006.01) C07F 7/18 (2006.01) C07F 9/568 (2006.01) C07F 9/6558 (2006.01)

Patent

CA 2063326

31,608- 00 ABSTRACT NOVEL 4-SUBTITUTED AZETIDINONEB AS PRECURSORS TO 2-SUBSTITUTED-2-CARBOXY CARBAPENEM ANTIBIOTICS AND A METHOD OF PRODUCING THEM New 4-substituted azetidinones having the formulae I and II: Image I II with R1, R2, R3, R4, R5 and X defined hereafter, which are intermediates for the preparation of carbapenem and carbacephem antibacterials and processes for producing such antibacterials through the utilization of an acid mediated ring closure reaction.

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