C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 239/72 (2006.01) A61K 31/498 (2006.01) A61P 35/00 (2006.01) C07D 239/86 (2006.01) C07D 239/94 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01)
Patent
CA 2703767
The invention relates to substituted 4-(tetrazol-5-yl)-quinazolute derivatives of the formula-1, or phannaceutically-acceptable salts thereof, which possess anti-proliferative activity such as anti-cancer activity and are accordingly useful in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of substituted 4-(tetrazol-5-yl)-quinazoline derivatives, to pharmaceutical compositions containing the compound and to its use in the manufacture of medica-ments for the production of an anti-proliferative effect in a warm- blooded animal such as man.
L'invention concerne des dérivés substitués de 4-(tétrazol-5-yl)-quinazoline de la formule I, ou des sels acceptables du point de vue pharmaceutique de ceux-ci, qui possèdent une activité anti-proliférative telle qu'une activité anti-cancéreuse et qui s'utilisent, par conséquent, dans des procédés de traitement du corps humain ou animal. L'invention concerne également des procédés pour la fabrication de dérivés substitués de 4-(tétrazol-5-yl)-quinazoline, des compositions pharmaceutiques contenant le composé et son utilisation dans la fabrication de médicaments pour la production d'un effet anti-prolifératif dans un animal à sang chaud tel que l'homme.
Adibhatla Kali Satya Bhujanga Rao
Ananthaneni Lakshmi
Chowdary Nannapaneni Venkaiah
Konakanchi Durga Prasad
Pula Subba Rao
Natco Pharma Limited
Robic
LandOfFree
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