Novel 7-deacetoxy baccatine iv derivative, and preparation...

C - Chemistry – Metallurgy – 07 – D

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C07D 305/14 (2006.01) C07D 493/18 (2006.01) C07F 7/18 (2006.01)

Patent

CA 2113186

A novel 7-deacetoxy baccatine IV derivative having formula (I), the preparation thereof from taxine B, and its use in preparing biologically active products, are described. In said formula (I), R is a hydrogen atom or acetyl radical and R1, R2, R3, and R4 are hydroxy-function protective groupings (preferably acetonides).

2113186 9302064 PCTABS00161 Nouveau dérivé de la 7-désacétoxy baccatine IV de formule (I), sa préparation à partir de la taxine B et son emploi pour préparer des produits biologiquement actifs. Dans la formule (I) R représente un atome d'hydrogène ou le radical acétyle, R1, R2, R3 et R4 représentent des groupements protecteurs de fonction hydroxy (de préférence des acétonides).

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