Novel acyl pseudodipeptides, preparation method and...

C - Chemistry – Metallurgy – 07 – C

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C07C 237/00 (2006.01) C07C 235/10 (2006.01) C07C 237/22 (2006.01) C07F 9/09 (2006.01)

Patent

CA 2337807

The invention concerns the field of chemistry and more particularly of therapeutic chemistry. It concerns N-acyl pseudodipeptides corresponding to general formula (I) wherein the substituents A, B, X, Y, R¿1?, R¿2?, n, m, p and q are as defined in the claims. The invention also concerns pharmaceutical compositions containing as active principle at least one compound of general formula (I) in acid form or salified by a mineral or organic base. Said compounds have interesting pharmacological properties which make them useful as medicines.

L'invention se rapporte au domaine de la chimie et plus particulièrement à celui de la chimie thérapeutique. Elle a pour objet des pseudodipeptides N- acylés répondant à la formule générale (I) dans laquelle les substituants A, B, X, Y, R1, R2, n, m, p et q ont les définitions fournies dans les revendications. L'invention concerne également les compositions pharmaceutiques renfermant à titre de principe actif au moins un composé de formule générale (I) sous forme acide ou salifiée par une base minérale ou organique. Les composés selon l'invention manifestent des propriétés pharmacologiques intéressantes qui les rendent utiles comme médicaments.

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