Novel adenosine derivatives

C - Chemistry – Metallurgy – 07 – H

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C07H 19/167 (2006.01) A61K 31/70 (2006.01) C07H 19/16 (2006.01)

Patent

CA 2113546

2113546 9323417 PCTABS00028 Novel substituted adenosine derivatives of formula (I), or a pharmaceutically acceptable salt thereof, wherein X represents hydrogen, halogen, amino, perhalomethyl, acetamido, cyano, C1-6-alkyl, C1-6-alkoxy, C1-6-alkylthio or C1-6-alkylamino; R1 is -NR2R3, -YR4, wherein Y is oxygen or sulphur; R2 is C1-6-alkyl; R3 is phenyl or C1-6-alkyl, which may be substituted with phenyl or phenoxy; R4 is naphthyl; partly saturated naphthyl; C1-6-alkyl, which may be substituted with phenoxy or phenyl, which may be substituted with nitro, halogen or amino; or C3-8-cycloalkyl, which may be substituted with phenyl or phenoxy, which have been found useful for treating central nervous system ailments.

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