Novel adenosine nitrates

Details Novel adenosine nitrates Novel adenosine nitrates

C - Chemistry, Metallurgy

07

H

260/229.5

C07H 19/16 (2006.01)

Patent

CA 1050534

A B S T R A C T Adenosine nitrates of the general formula: Image (I) wherein R1 and R2 represent a hydrogen atom or a nitro group with at least one of R1 and R2 representing a nitro group; and R5 represents a hydroxy, lower alkoxy, amino, (lower alkyl)amino, di-(lower alkyl)amino, [di-(lower alkyl)amino-(lower alkyl)]amino, (nitrato-lower alkyl)amino, aryl-(lower alkyl)amino or cycloalkylamino group or a nitrogen-containing heterocyclic ring which is bonded via a nitrogen atom, and physiologically acceptable acid addition salts thereof. The compounds are useful as therapeutical agents with effects on the heart and on the circulatory-dynamics and process for the preparation thereof.

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