A - Human Necessities – 61 – K
Patent
A - Human Necessities
61
K
A61K 31/16 (2006.01) A61K 31/165 (2006.01) A61K 31/215 (2006.01) A61K 31/35 (2006.01) A61K 31/415 (2006.01) A61K 31/66 (2006.01) A61K 31/70 (2006.01)
Patent
CA 2337859
Drugs characterized by containing hydroxamic acid derivatives as the active ingredient which are efficacious in treating and/or preventing allergies, in particular, type I and/or type II allergies, etc. These drugs exert therapeutic and/or preventive effects on inflammation, rhinitis, conjunctivitis, bronchial asthma, atopic dermatitis (dermatitis, enteritis, etc.) and allergic digestive inflammation. Use of these drugs achieves the effects of: (A) inhibiting the proliferation of colonies of blood cells (lymphocytes, etc.) in an affected part; and/or (B) relieving inflammation caused by the migration, infiltration, accumulation, etc. of blood cells (lymphocytes, etc.) into an affected part; and/or (C) regulating the pathophysiological functions of cells such as blood cells (lymphocytes, etc.), Langerhans cells and dendritic cells; and/or (D) regulating the production of antibodies, in particular, IgE in the plasma, thus being useful in treating and/or preventing diseases or pathological conditions in the affected parts.
L'invention concerne des médicaments caractérisés en ce qu'ils renferment des dérivés d'acide hydroxamique tenant lieu de principe actif. Il s'agit de médicaments efficaces pour le traitement et/ou la prévention des allergies, en particulier les allergies de type I et/ou II, etc. Lesdits médicaments ont une action thérapeutique et/ou préventive contre l'inflammation, la rhinite, la conjonctivite, l'asthme, les maladies atopiques (dermite, entérite, etc.) et l'inflammation allergique du système digestif. L'utilisation des médicaments considérés produit les effets suivants: (A) inhibition de la prolifération des colonies de globules sanguins (lymphocytes, etc.) dans la partie du corps affectée; et/ou (B) apaisement de l'inflammation causée par la migration, l'infiltration, l'accumulation, etc., des globules sanguins (lymphocytes, etc.) dans la partie du corps affectée; et/ou (C) régulation des fonctions pathophysiologiques de cellules comme les globules sanguins (lymphocytes, etc.), les cellules de Langerhans et les cellules dendritiques ; et/ou (D) régulation de la production d'anticorps, en particulier l'immoglobuline E (IgE) dans le plasma. Les médicaments en question sont donc utiles pour le traitement et/ou la prévention des maladies ou des affections pathologiques affectant telle ou telle partie du corps.
Fujisawa Tetsunori
Igeta Katsuhiro
Matsuo Tetsu
Odake Shinjiro
Oku Tohru
Daiichi Fine Chemical Co. Ltd.
Fetherstonhaugh & Co.
Fuji Yakuhin Kogyo Kabushiki Kaisha
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