Novel aggrecanase molecules

Details Novel aggrecanase molecules Novel aggrecanase molecules

C - Chemistry, Metallurgy

12

N

C12N 9/64 (2006.01) C07K 16/40 (2006.01) C12N 5/10 (2006.01) C12N 15/52 (2006.01)

Patent

CA 2426463

Aggrecanase proteins and the nucleotides sequences encoding them as well as processes for producing them are disclosed. Methods for developing inhibitors of the aggrecanase enzymes and antibodies to the enzymes for treatment of conditions characterized by the degradation of aggrecan are also disclosed.

L'invention concerne des protéines aggrécanase, les séquences nucléotides qui les codent et leurs procédés de production. L'invention traite également de procédés d'élaboration d'inhibiteurs des enzymes aggrécanase et d'anticorps aux enzymes pour le traitement d'états caractérisés par la dégradation de l'aggrécan.

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