Novel alicyclic imidazoles as h3 agents

Details Novel alicyclic imidazoles as h3 agents Novel alicyclic imidazoles as h3 agents

A - Human Necessities

61

K

A61K 31/4164 (2006.01) C07D 233/54 (2006.01) C07D 233/64 (2006.01)

Patent

CA 2419073

Alicyclic imidazole compounds; pharmaceutically active compositions containing such compounds; and the use of such compounds in formulations for the control or prevention of disease states in which histamine H3 receptors are involved, such as allergy, inflammation, hypotension, glaucoma, sleeping disorders, states of hyper- and hypo-motility of the gastro-intestinal tract, cardiovascular disease, hypo- and hyper-activity of the central nervous system, Alzheimer's, schizophrenia, obesity and migraines are disclosed.

L'invention concerne des composés d'imidazole alicyclique, des compositions pharmaceutiquement actives contenant ces composés, et l'utilisation de ces composés dans des préparations de traitement ou de prévention d'états pathologiques dans lesquels interviennent les récepteurs de l'histamine H¿3?, tels que l'allergie, l'inflammation, l'hypotension, le glaucome, les troubles du sommeil, les états d'hyper- ou d'hypomotilité du tractus gastro-intestinal, les maladies cardiovasculaires, les états d'hypo- ou d'hyperactivité du système nerveux central, la maladie d'Alzheimer, la schizophrénie, l'obésité ou les migraines.

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