Novel alpha-mannosidase inhibitors

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 221/04 (2006.01) A61K 31/435 (2006.01) A61K 31/70 (2006.01) C07H 19/02 (2006.01) C07H 19/048 (2006.01)

Patent

CA 2116224

(4S-(4.alpha., 4a.beta., 5.beta., 6.alpha., 7.alpha., 7a.alpha.)]-Octahydro-1H- 1-pyrindine-4,5,6,7-tetrols and [4R-(4.alpha., 4a.alpha., 5.alpha., 6.beta., 7.beta., 7a.beta.)]-octahydro-1H- 1-pyrindine-4,5,6,7-tetrols are useful as inhibitors of alpha-mannosidase and are useful immunostimulants, chemoprotective and radioprotective agents and antimetastatic agents.

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