Novel amination process

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 241/02 (2006.01) C07D 405/04 (2006.01)

Patent

CA 2560790

Provided herein are novel processes for the preparation of intermediates that may be useful in the preparation of 5-Ht1b receptor antagonist useful in the treatment of depression, anxiety and other related diseases. The present processes may offer improved yields, purity, ease of preparation and isolation of intermediates and final product and more industrially useful reaction conditions and workability.

La présente invention concerne de nouveaux procédés destinés à l'élaboration d'intermédiaires susceptibles de convenir à l'élaboration de l'antagoniste du récepteur 5-Ht¿1b? convenant au traitement de la dépression, de l'anxiété et des pathologies connexes. Les traitements de l'invention sont susceptibles d'apporter des améliorations quant à l'efficacité, la pureté, et la facilité d'élaboration et d'isolation des intermédiaires et du produit final, et de mieux convenir aux conditions industrielles pratiques de réaction utile, et de mise en oeuvre.

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