C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/438 (2006.01) A61K 31/519 (2006.01) C07D 491/10 (2006.01)
Patent
CA 2502477
The invention describes compounds of the general formula (I), a process for their manufacture, medicaments containing them and their manufacture as well as the use of these compounds as pharmaceutically active agents. The said compounds show activity as protein kinase inhibitors, in particular src family tyrosine kinase inhibitors, and may therefore be usefull for the treatment of diseases mediated by said tyrosine kinases.
L'invention concerne des composés de formule générale (I), leur procédé de fabrication, des médicaments les contenant et leur fabrication, ainsi que l'utilisation desdits composés en tant qu'agents pharmaceutiquement actifs. Lesdits composés présentent une activité en tant qu'inhibiteurs des protéines kinases, en particulier en tant qu'inhibiteurs des tyrosines kinases de la famille des Src, et peuvent par conséquent être utiles dans le traitement de maladies induites par lesdites tyrosines kinases.
Cai Jianping
Dimoudis Nikolaos
Honold Konrad
Luk Kin-Chun
Scheiblich Stefan
F. Hoffmann-La Roche Ag
Gowling Lafleur Henderson Llp
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