Novel aminoalcohol-substituted aryldihydroisoquinolinones,...

C - Chemistry – Metallurgy – 07 – D

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C07D 217/24 (2006.01) A61K 31/435 (2006.01) A61P 5/00 (2006.01) C07D 401/12 (2006.01) C07D 451/06 (2006.01) C07D 453/02 (2006.01) C07D 455/06 (2006.01) C07D 471/04 (2006.01)

Patent

CA 2636617

The invention relates to aminoalcohol-substituted aryldihydroisoquinolinones and their derivatives, and their physiologically tolerated salts and physiologically functional derivatives, their preparation, medicaments comprising at least one aminoalcohol-substituted aryldihydroisoquinolinone of the invention or its derivative, and the use of the aminoalcohol- substituted aryldihydroisoquinolinones of the invention and their derivatives as MCH antagonists.

L'invention concerne des aryldihydroisoquinolinones à substitution amino-alcool et leurs dérivés, ainsi que leurs sels tolérés physiologiquement et leurs dérivés présentant une fonctionnalité sur le plan physiologique. L'invention concerne également la préparation de tels composés, des médicaments comprenant au moins une aryldihydroisoquinolinone à substitution amino-alcool de l'invention ou son dérivé, et l'utilisation des aryldihydroisoquinolinones à substitution amino-alcool de l'invention et de leurs dérivés en tant qu'agonistes de MCH.

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