Novel aminoindanes

C - Chemistry – Metallurgy – 07 – C

Patent

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Details

C07C 229/36 (2006.01) A61K 31/195 (2006.01) A61K 31/275 (2006.01) A61K 31/4166 (2006.01) C07C 227/00 (2006.01) C07C 229/46 (2006.01) C07C 229/50 (2006.01) C07C 255/26 (2006.01) C07C 255/42 (2006.01) C07C 255/47 (2006.01) C07D 233/40 (2006.01) C07D 233/76 (2006.01) C07D 235/02 (2006.01)

Patent

CA 2376470

The present invention relates to therapeutically active novel aminoindanes of formula (I). Also provided is a method of preparing compounds of formula (I), and pharmaceutical compositions comprising the compounds. The novel compounds act as modulators of metabotropic glutamate receptors and, as such, are useful in treating diseases of the central nervous system related to the metabotropic glutamate receptor system.

La présente invention concerne les nouveaux amino-indanes à activité thérapeutique de la formule (I). L'invention se rapporte également à un procédé permettant de préparer des composés de la formule (I) et à des compositions pharmaceutiques renfermant ces composés. Les nouveaux composés de l'invention agissent comme modulateurs des récepteurs métabotropiques du glutamate et, en tant que tels, ils sont utilisés pour traiter les maladies du système nerveux central liées au système des récepteurs métabotropiques du glutamate.

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