C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 263/48 (2006.01) A61K 31/42 (2006.01) A61K 31/421 (2006.01) A61K 31/422 (2006.01) A61K 31/425 (2006.01) A61K 31/426 (2006.01) A61K 31/427 (2006.01) A61K 31/4439 (2006.01) A61K 31/4709 (2006.01) A61P 9/00 (2006.01) A61P 17/00 (2006.01) A61P 17/06 (2006.01) A61P 19/02 (2006.01) A61P 27/02 (2006.01) A61P 29/00 (2006.01) A61P 35/00 (2006.01) C07D 277/46 (2006.01) C07D 413/04 (2006.01) C07D 413/14 (2006.01) C07D 417/04 (2006.01)
Patent
CA 2336848
The present invention relates to compounds which inhibit tyrosine kinase enzymes, compositions which contain tyrosine kinase inhibiting compounds and methods of using tyrosine kinase inhibitors to treat tyrosine kinase-dependent diseases and conditions such as angiogenesis, cancer, atherosclerosis, diabetic retinopathy or autoimmune diseases, in mammals.
L'invention concerne des composés inhibant l'enzyme tyrosine kinase, des compositions contenant ces composés inhibant la tyrosine kinase, ainsi que des procédés d'utilisation de ces inhibiteurs pour traiter des maladies et états associés à la tyrosine kinase, tels que l'angiogenèse, le cancer, l'athérosclérose, la rétinopathie diabétique ou les maladies auto-immunes, chez des mammifères.
Fraley Mark E.
Hoffman William F.
Huckle William R.
Hungate Randall W.
Kendall Richard L.
Merck & Co. Inc.
Ogilvy Renault Llp/s.e.n.c.r.l.,s.r.l.
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