C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 471/04 (2006.01) A61K 31/4439 (2006.01) A61K 31/444 (2006.01) C07D 401/14 (2006.01) C07D 409/14 (2006.01)
Patent
CA 2356349
The present invention relates to compounds which inhibit tyrosine kinase enzymes, compositions which contain tyrosine kinase inhibiting compounds and methods of using tyrosine kinase inhibitors to treat tyrosine kinase-dependent diseases and conditions such as angiogenenesis, cancer, atherosclerosis, diabetic retinopathy, and the like in mammals.
La présente invention concerne des composés d'inhibition des enzymes tyrosine-kinase, des compositions qui contiennent des composés d'inhibition de la tyrosine-kinase et des procédés d'utilisation de composés d'inhibition de la tyrosine-kinase qui permettent de traiter les troubles liés à la tyrosine-kinase et les états pathologiques tels que l'angiogénèse, le cancer, l'athérosclérose, la rétinopathie diabétique, et analogue chez les mammifères.
Fraley Mark E.
Hungate Randall W.
Tebben Andrew J.
Gowling Lafleur Henderson Llp
Merck & Co. Inc.
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