C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/04 (2006.01) A61K 31/343 (2006.01) A61K 31/4045 (2006.01) A61K 31/4184 (2006.01) A61K 31/423 (2006.01) A61K 31/428 (2006.01) A61K 31/47 (2006.01) A61K 31/517 (2006.01) C07D 209/08 (2006.01) C07D 209/30 (2006.01) C07D 215/30 (2006.01) C07D 215/38 (2006.01) C07D 215/48 (2006.01) C07D 217/02 (2006.01) C07D 235/10 (2006.01) C07D 235/12 (2006.01) C07D 235/18 (2006.01) C07D 237/28 (2006.01) C07D 239/74 (2006.01) C07D 263/57 (2006.01) C07D 277/64 (2006.01) C07D 277/66 (2006.01) C07D 305/14 (2006.01) C07D
Patent
CA 2498644
Heterocyclic amidines with anti-inflammatory and analgesic activity that inhibit nitrogen oxide production, of formula (I): (See formula I) in which: - G1 and G2 are hydrogen, halogen, hydroxyl, C1-C4 alkoxy, C1-C4 alkyl, and an amidino substituent of formula Q, provided that, for each compound of formula (I), only one of the two substituents G1 or G2 is an amidino substituent of formula Q: (See formula Q) and in which the substituents W, Y and X are combined to form 9- or 10-membered bicyclic heteroaromatic derivatives containing up to 2 hetero atoms in the same ring; and - Z is an aryl or heteroaryl group, a linear or branched C1-C6 alkyl or alkenyl chain, a C1-C4 alkyl-aryl group or a C1-C4 alkyl-heteroaryl group.
Artusi Roberto
Giordani Antonio
Makovec Francesco
Mandelli Stefano
Rovati Lucio Claudio
Macrae & Co.
Rottapharm S.p.a.
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