Novel anti-proliferative effects of sodium butyrate

A - Human Necessities – 61 – K

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A61K 31/19 (2006.01)

Patent

CA 2192854

The present invention provides a method of inhibiting the proliferation of smooth muscle cells comprising the step of contacting said cells with a pharmacologically effective amount of sodium butyrate. Also provided is a method of inhibiting the formation of cerebrovascular disease in a human comprising the step of administering to said human a pharmacologically effective amount of sodium butyrate.

La présente invention concerne un procédé pour inhiber la prolifération des cellules des muscles lisses, consistant à mettre en contact ces cellules avec une quantité pharmacologiquement efficace de butyrate de sodium. L'invention concerne également une méthode destinée à inhiber des maladies cérébro-vasculaires chez l'homme, consistant à administrer au patient une quantité pharmacologiquement efficace de butyrate de sodium.

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