C - Chemistry – Metallurgy – 07 – K
Patent
C - Chemistry, Metallurgy
07
K
C07K 7/50 (2006.01) A61K 38/12 (2006.01) C07K 9/00 (2006.01) A61K 38/00 (2006.01)
Patent
CA 2318394
Novel antibacterial agents that act as multibinding agents are disclosed. The compounds of the invention comprise from 2-10 ligands covalently connected, each of said ligands being capable of binding to a transglycosylase enzyme substrate thereby modulating the biological processes/functions thereof.
La présente invention concerne de nouveaux agents antibactériens qui agissent comme agents multiliaison. Les composés selon l'invention comprennent de 2 à 10 ligands à liaison covalente, chacun desdits ligants étant capable de se lier à un substrat d'enzyme de transglycosylase et, par la même, de moduler les processus/fonctions biologiques dudit substrat.
Chen Qi-Qi
Griffin John H.
Jenkins Thomas E.
Judice J. Kevin
Linsell Martin S.
Advanced Medicine Inc.
Theravance Inc.
Torys Llp
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