Novel antihistaminic piperidine derivatives and...

Details Novel antihistaminic piperidine derivatives and... Novel antihistaminic piperidine derivatives and...

C - Chemistry, Metallurgy

07

D

C07D 211/22 (2006.01) A61K 31/445 (2006.01) C07C 69/738 (2006.01) C07C 259/06 (2006.01)

Patent

CA 2336380

This invention relates to novel piperidine derivatives of formula (I) and a process for the preparation thereof, wherein R1 is H or C1-C6alkyl wherein the C1-C6alkyl moiety is straight or branched; R2 is -COOH or -COOalkyl wherein the alkyl moiety has from 1 to 6 carbon atoms and is straight or branched; or stereoisomers or pharmaceutically acceptable acid addition salt thereof.

La présente invention concerne des dérivés de pipéridine repérsentés par la formule générale (I) et certains de leurs stéréoisomères ou de leurs sels d'addition acides pharmaceutiquement admis. Dans la formule générale, R1 est H ou C1-C6alkyle, le groupe fonctionnel C1-C6alkyle étant droit ou ramifié. R2 est -COOH ou ou -COOalkyle auquel cas le groupe fonctionnel alkyle, qui porte de 1 à 6 atomes de carbone, peut être droit ou ramifié.

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