Novel antimicrobial peptides and use thereof

Details Novel antimicrobial peptides and use thereof Novel antimicrobial peptides and use thereof

C - Chemistry, Metallurgy

07

K

C07K 7/06 (2006.01) A61K 38/08 (2006.01) A61K 38/10 (2006.01) A61K 38/36 (2006.01) A61P 31/04 (2006.01) A61P 31/12 (2006.01) A61P 33/00 (2006.01) C07K 7/08 (2006.01) C07K 14/745 (2006.01)

Patent

CA 2637221

The invention relates to a molecule comprising at least the amino acid se- quence X1 X2 X3 X4 X5 X6 W X8 X9 X10 wherein X4,6,9 is any amino acid residue, X1 is I, L or V, X2 is not C, X3 is A, E, Q, R or Y, X5 is not R, X8 is I or L, X10 is not H and wherein said molecule have a length of from about 10 to about 100 amino acid residues or an analogue thereof. The invention also relates to compositions comprising said molecule and use of the molecule and/or composition of the inven- tion to combat microorganisms, such as bacteria, viruses, fungi, including yeast, and parasites.

L'invention concerne une molécule comprenant au moins la séquence d'acides aminés X1 X2 X3 X4 X5 X6 W X8 X9 X10, dans laquelle X4,6,9 représente tout résidu d'acide aminé, X1 représente I, L ou V, X2 ne représente pas C, X3 représente A, E, Q, R ou Y, X5 ne représente pas R, X8 représente I ou L, X10 ne représente pas H, ladite molécule ayant une longueur comprise entre environ 10 et environ 100 résidus d'acide aminé ou analogue. L'invention concerne également des compositions comprenant ladite molécule et l'utilisation de la molécule et/ou de la composition selon l'invention pour lutter contre des microorganismes, tels que les bactéries, les virus, les champignons, y compris les levures, et les parasites.

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