C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 409/12 (2006.01) A61K 31/4015 (2006.01) A61K 31/4025 (2006.01) A61P 7/02 (2006.01) C07D 207/26 (2006.01) C07D 405/12 (2006.01) C07D 409/14 (2006.01)
Patent
CA 2599021
The invention relates to novel substituted pyrrolidines of general formula (I), wherein A, X, B and R1 to R9 are such as defined in the claim 1, and to the tautomers, enantiomers, diastereomers, mixtures and the salts thereof, in particular, the salts thereof physiologically compatible with acids or organic or inorganic bases, wherein said compounds exhibit antithrombotic and Xa- inhibiting actions.
L'invention a pour objet de nouvelles pyrrolidinones substituées, de formule générale (I) dans laquelle A, X, B et R1 à R9 sont tels que définis dans la revendication 1, ainsi que leurs tautomères, leurs énantiomères, leurs diastéréoisomères, leurs mélanges et leurs sels, en particulier, leurs sels physiologiquement compatibles avec des acides ou des bases inorganiques ou organiques, ces composés présentant un effet antithrombotique et un effet inhibant le facteur Xa.
Dahmann Georg
Gerlach Kai
Nar Herbert
Pfau Roland
Priepke Henning
Boehringer Ingelheim International Gmbh
Fetherstonhaugh & Co.
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