Novel application of 4-carbamoyl-1- b -d-ribofuranosyl...

A - Human Necessities – 61 – K

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A61K 31/70 (2006.01) A61K 31/415 (2006.01) C07H 19/052 (2006.01)

Patent

CA 2042752

ABSTRACT OF THE DISCLOSURE A composition for the treatment or prevention of multiple sclerosis is disclosed. It comprises mizoribine (4-carbamoyl-1-.beta.-D-ribofuranosyl imidazolium-5-olate) as the effective component. It is a safe drug, exhibiting a minimal degree of side-effects, and thus can be administered over a long period of time. Administration of the drug, usually 1-20 mg/kg (body weight) per day for adults, improves the functional disturbances of multiple sclerosis.

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