C - Chemistry – Metallurgy – 07 – H
Patent
C - Chemistry, Metallurgy
07
H
C07H 17/075 (2006.01) A61K 31/70 (2006.01)
Patent
CA 2317951
The invention concerns compounds of formula (I), in which Y is oxygen, N-Nalc¿1? or NOalc¿2?; X represents hydrogen, hydroxyl, alkyl, alkenyl, alkynyl, alkoxy, CONOR or NRcRd, Rc and Rd being hydrogen or alkyl; Z represents hydrogen, halogen or free, etherified or esterified OH; R¿2? hydrogen or halogen; R¿3? hydrogen, alkyl or halogen; R hydrogen or alkyl; R¿1? hydrogen, alkyl, alkenyl or alkynyl; R¿5? hydrogen or O-alkyl; R¿6? alkyl or CH¿2?-O-alkyl and R¿7? hydrogen or alkyl; or R¿6? and R¿7? form with the carbon atom which bears them a cyclic radical containing up to 8 carbon atoms. The compounds of formula (I) have antibiotic properties.
L'invention a pour objet les composés de formule (I), dans laquelle: Y oxygène, N-Nalc1 ou NOalc2; X hydrogène, hydroxyle, alkyle, alkényle, alkynyle, alkoxy, CONOR ou NRcRd, Rc et Rd hydrogène ou alkyle; Z hydrogène, halogène ou OH libre, éthérifié ou estérifié; R2 hydrogène ou halogène; R3 hydrogène, alkyle ou halogène; R hydrogène ou alkyle; R1 hydrogène, alkyle, alkényle ou alkynyle; R5 hydrogène ou O-alkyle; R6 alkyle ou CH2-O-alkyle et R7 hydrogène ou alkyle, ou bien R6 et R7 forment avec l'atome de carbone qui les portent un radical cyclique renfermant jusqu'à 8 atomes de carbone. Les composés de formule (I) présentent des propriétés antibiotiques.
Haesslein Jean-Luc
Klich Michel
Laurin Patrick
Musicki Branislav
Periers Anne-Marie
Hoechst Marion Roussel
Novexel
Robic
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