Novel aromatic derivatives substituted by a ribose, their...

C - Chemistry – Metallurgy – 07 – H

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C07H 17/075 (2006.01) A61K 31/70 (2006.01) C07D 311/54 (2006.01) C07D 311/56 (2006.01) C07H 15/04 (2006.01) C07H 15/18 (2006.01)

Patent

CA 2258152

The invention discloses the compounds of formula (I): R1 = H, OH, alkyl, alkenyl or alkynyl optionally substituted or alkoxy; R2 = H, Hal; R3 = H, alkyl, Hal, R4 = (a) where Rg and Rh are H, alkyl, an aryl heterocycle; R5 = H or O-alkyl; R6 = alkyl or CH2-O-alkyl; R7 = H or alkyl. The compounds of formula (I) have antibiotic properties.

L'invention a pour objet les composés de formule (I), où R1 = H, OH, alkyle, alkényle ou alkynyle éventuellement substitué ou alkoxy; R2 = H, Hal; R3 = H, alkyle, Hal; R4 = (a), Rg et Rh: H, alkyle, aryle hétérocycle; R5 = H ou O-alkyle; R6 = alkyle ou CH2-O-alkyle; R7 = H ou alkyle. Les composés de formule (I) présentent des propriétés antibiotiques.

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