Novel aryl-pyridazines

Details Novel aryl-pyridazines Novel aryl-pyridazines

C - Chemistry, Metallurgy

07

D

C07D 491/147 (2006.01) A61K 31/415 (2006.01) A61K 31/425 (2006.01) A61K 31/435 (2006.01) A61K 31/50 (2006.01) C07D 231/54 (2006.01) C07D 237/26 (2006.01) C07D 237/36 (2006.01) C07D 471/04 (2006.01) C07D 491/04 (2006.01) C07D 491/052 (2006.01) C07D 491/14 (2006.01) C07D 495/04 (2006.01) C07D 495/14 (2006.01)

Patent

CA 2263586

Use of a compound of formula (I) wherein, A, A1, A2 and A3 are all CH or CR4 or one of A, A1, A2 or A3 is nitrogen and the others are all CH or CR4; Ar1 and Ar2 are independently phenyl, pyridyl, benzothiazolyl, quinolyl or quinoxalinyl all of which are optionally substituted by one or more substituents, X, Y, Z, R1, R2, R3, R4 are as described in the specification or a pharmaceutically acceptable derivative thereof in the manufacture of a medicament for the treatment of an allergic or an inflammatory condition.

L'invention concerne un composé selon la formle (I). Dans cette dernière, A, A?1¿, A?2¿ et A?3¿ sont tous CH ou CR?4¿ ou un élément parmi A, A?1¿, A?2¿ ou A?3¿ est de l'azone et les autres sont tous CH ou CR?4¿. Ar?1¿ et Ar?2¿ représentent, indépendamment, phényle, pyridyle, benzothiazolyle, quinolyle ou quinoxalinyle, tous éventuellement substitués par un ou plusieurs substituents. X, Y, Z, R?1¿, R?2¿, R?3¿, R?4¿ sont tels que définis dans le descriptif, ou un dérivé pharmaceutiquement acceptable de ce dernier dans la fabrication d'un médicament pour le traitement des allergies ou des inflammations.

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