Novel azacycly-substituted arylthienopyrimidinones, process...

C - Chemistry – Metallurgy – 07 – D

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C07D 495/04 (2006.01) A61K 31/506 (2006.01) A61K 31/519 (2006.01) A61P 3/00 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) C07D 403/10 (2006.01) C07D 491/04 (2006.01)

Patent

CA 2636605

The invention relates to azacyclyl-substituted arylthienopyrimidinones and their derivatives of formula (I), and their physiologically tolerated salts and physiologically functional derivatives, their preparation, medicaments comprising at least one azacyclyl-substituted arylthienopyrimidinone of the invention or its derivative, and the use of the azacyclyl-substituted aryithienopyrimidinones of the invention and their derivatives as MCH antagonists.

La présente invention concerne des arylthiénopyrimidinones substituées par azacyclyle ainsi que leurs dérivés de formule (I), et leurs sels de qualité physiologique et leurs dérivés fonctionnels au niveau physiologique, leur synthèse, des médicaments comprenant au moins une arylthiénopyrimidinone substituée par azacyclyle selon l'invention ou son dérivé, et l'emploi des arylthiénopyrimidinones substituées par azacyclyle selon l'invention et de leurs dérivés en tant qu'antagonistes de la MCH.

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