Novel azetidine compounds useful in the treatment of...

C - Chemistry – Metallurgy – 07 – D

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C07D 487/04 (2006.01) A61K 31/397 (2006.01) A61K 31/4985 (2006.01) A61K 31/5383 (2006.01) A61P 1/00 (2006.01) C07D 205/04 (2006.01) C07D 405/12 (2006.01) C07D 471/04 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2624491

The present invention relates to new azetidine compounds, to pharmaceutical compositions cotaining them and the use of said compounds in in the treatment of functional gastrointestinal disorders, IBS and functional dyspepsia. The compounds are neurokinin (NK) antagonists . The present invention further relates to processes for the preparation of the compounds.

La présente invention concerne de nouveaux composés d'azétidine, des compositions pharmaceutiques contenant ces composés, et l'utilisation de ces composés dans le traitement de troubles gastro-intestinaux fonctionnels, de l'IBS et de la dyspepsie fonctionnelle. Les composés de l'invention sont des antagonistes de la neurokinine (NK). L'invention concerne en outre des méthodes de préparation desdits composés.

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