Novel bacteriocin compositions for use as enhanced broad range

Details Novel bacteriocin compositions for use as enhanced broad range Novel bacteriocin compositions for use as enhanced broad range

A - Human Necessities

01

N

167/103, 167/5.1

A01N 63/02 (2006.01) A61K 38/16 (2006.01)

Patent

CA 2028140

Broad range bacteriocin compositions are provided. The compositions can be dissolved or suspended in a suitable solvent or matrix and are more active towards a broader range of bacteria than are any of the component parts. The dissolved or su- spended compositions constitute enhanced broad range bactericides. The compositions include lysostaphin and lanthionine con- taining peptide bacteriocin; lysostaphin, a lanthionine containing peptide bacteriocin and a chelating agent; and lysostaphin, a lanthionine containing peptide, a chelating agent and a surfactant. Each component is present in the enhanced broad range bac- tericide in sufficient amount such that the bactericide is more effective against staphylococci than is lysostaphin alone and is more effective at treating and preventing a broad range of microbial infections. Methods of treating bacterial infections using said compositions and bactericides are provided.

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