Novel bee venom polypeptides and methods of use thereof

C - Chemistry – Metallurgy – 07 – K

Patent

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Details

C07K 19/00 (2006.01) A61K 38/17 (2006.01) A61K 39/395 (2006.01) C07K 1/14 (2006.01) C07K 14/435 (2006.01) C07K 16/00 (2006.01) A61K 38/00 (2006.01)

Patent

CA 2398979

The present invention provides novel protein named Api m 6. Api m 6 was identified in bee venom and is found in four isoforms, each about 8 kD. The purified Api m 6 can be used to modulate immune responses, e.g., in individuals hypersensitive to bee venom.

L'invention concerne une protéine dénommée Api m 6. L'Api m 6 a été identifiée dans du venin d'abeille sous quatre isoformes, chacune de 8 kD environ. On peut utiliser l'Api m 6 purifiée afin de moduler des réponses immunes, par exemple chez des sujets hypersensibles au venin d'abeille.

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