Novel benz-acyl-benzimidazole-2-derivatives

Details Novel benz-acyl-benzimidazole-2-derivatives Novel benz-acyl-benzimidazole-2-derivatives

C - Chemistry, Metallurgy

07

D

260/280, 260/305

C07D 235/12 (2006.01) C07C 45/46 (2006.01) C07C 49/807 (2006.01) C07C 49/813 (2006.01)

Patent

CA 1098526

Abstract of the Disclosure Novel benz-acyl-benzimidazole-2-derivatives of the formula Image (I) wherein R denotes carboxy, esterified carboxy, hydroxy- methyl or hydroxymethyl etharified with a lower alkanol or a di-lower alkylamino-lower alkanol or esteriried with a lower alkane carboxylic acid or with a benzoic acid, R1 denotes an aliphatic, cycloaliphatic, aromatic araliphatic furyl, thienyl, pyridyl or furyl-lower alkyl, thienyl-lower alkyl or pyridyl-lower alkyl radical, R2 denotes hydrogen or an aliphatic radical and Ph denotes a 1,2- phenylene group which may, in addition to the group R1-C(= O)-, be substituted by lower alkyl, lower alkoxy, hydroxyl and/or halogen, with the proviso that R1 contains at least 2 carbon atoms, if Ph is otherwise unsubstituted, R2 deno- tes ethyl and R denotes acetoxymethyl, and salts of such compounds having salt-forming propertles are useful as anti-allergic agents. - 1 -

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