C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 417/06 (2006.01) A61K 31/155 (2006.01) A61K 31/426 (2006.01) A61P 19/10 (2006.01) C07D 277/22 (2006.01) C07D 277/28 (2006.01)
Patent
CA 2694639
The present invention relates to novel benzamidine derivatives, a process for the preparation thereof and a pharmaceutical composition for preventing or treating osteoporosis comprising the same. The benzamidine derivatives of the present invention effectively inhibit osteoclast differentiation at an extremely low concentration, and thus can be advantageously used for the prevention and treatment of osteoporosis.
L'invention concerne de nouveaux dérivés de benzamidine, un procédé de préparation correspondant et une composition pharmaceutique les contenant qui permet de prévenir ou de traiter l'ostéoporose. Ces dérivés inhibent de manière efficace la différentiation des ostéoclastes à un niveau de concentration extrêmement faible, et peuvent donc être utilisés de manière avantageuse dans la prévention et le traitement de l'ostéoporose.
Hwang Yun Ha
Jin Young Goo
Kim Bo Kyung
Kim Ki Yoon
Ku Sae Kwang
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Dong Wha Pharmaceutical Co. Ltd.
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