C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 277/22 (2006.01) A61K 31/155 (2006.01) A61K 31/426 (2006.01) A61P 19/10 (2006.01)
Patent
CA 2637336
The present invention relates to a novel benzamidine derivative, a process for the preparation thereof, and a pharmaceutical composition comprising the same. The benzamidine derivative of the present invention effectively inhibits osteoclast differentiation at an extremely low concentration, and greatly increases the trabecular bone volume, and thus it can be advantageously used for the prevention and treatment of osteoporosis.
L'invention concerne un nouveau dérivé de benzamidine, son procédé de fabrication et une composition pharmaceutique le renfermant. Même en très faible concentration, ce dérivé de benzamidine inhibe efficacement la différentiation des ostéoclastes et accroît considérablement le volume osseux trabéculaire. Il peut, ipso facto, s'utiliser avantageusement pour la prévention et le traitement de l'ostéoporose.
Hwang Yun Ha
Jin Young Goo
Ku Sae Kwang
Lee Jin Soo
Lee Ki Young
Bereskin & Parr Llp/s.e.n.c.r.l.,s.r.l.
Dong Wha Pharmaceutical Co. Ltd.
Dong Wha Pharmaceutical Ind. Co. Ltd.
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