Novel benzo[b][1,8]naphtyridine derivatives; process for...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/47 (2006.01)

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CA 2007760

Nouveaux dérivés de benzo[b]naphtyridine-1,8 de formule générale (T) dans laquelle R est un atome d'hydrogène ou un radical alcoyles fluoroalcoyle, cycloalcoyle (3 à 6 C), alcoyloxy, alcoylamino ou un radical protecteur d'amine, et soit Hal est un atome de fluor de chlore ou de brome, et R' est un atome d'hydrogène, soit Hal et R' sont simultanément des atomes de fluor, leurs sels, Leur préparation et les compositions qui les contiennent. Ces nouveaux produits sont utiles comme antimicrobiens à usage local ou comme intermédiaires de synthèses. (voir formule I)

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