Novel benzofuran derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 405/04 (2006.01) A61K 31/443 (2006.01) A61K 31/4436 (2006.01) A61P 5/28 (2006.01) A61P 5/32 (2006.01) A61P 35/00 (2006.01) C07D 405/14 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2409096

The invention relates to novel benzofuran derivatives of the general formula (I) or salts thereof (wherein Py is 2-, 3-, or 4-pyridyl; and R is substituted or unsubstituted phenyl or a substituted or unsubstituted aromatic heterocyclic group). The invention also relates to inhibitors against steroid 17 .alpha. hydroxylase and/or C17-20 lyase or pharmaceutical compositions which contain the derivatives (I) or the salts.

L'invention concerne de nouveaux dérivés de benzofurane de formule générale (I) ou des sels de ces derniers, formule dans laquelle Py représente 2-, 3- ou 4-pyridyle, et R représente un phényle substitué ou non ou un groupe hétérocyclique aromatique substitué ou non. L'invention concerne également des inhibiteurs dirigés contre la 17.alpha. hydroxylase stéroïde et/ou la lyase C17-20, ou des compositions pharmaceutiques qui contiennent les dérivés (I) ou les sels.

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