Novel benzothiophene derivative

Details Novel benzothiophene derivative Novel benzothiophene derivative

C - Chemistry, Metallurgy

07

D

C07D 409/02 (2006.01) A61K 31/38 (2006.01) A61K 31/395 (2006.01) C07D 333/52 (2006.01) C07D 333/54 (2006.01) C07D 333/56 (2006.01) C07D 333/62 (2006.01) C07D 413/12 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2123514

A benzothiophene derivative represented by the formula Image (in which R1 is H, OH, alkoxy, acyloxy or carbomoyloxy; R2 is halo, alkyl, cycloalkyl or cycloalkenyl; R3 and R4 are H or alkyl or together with the N atom form heterocyclic ring; A is 0 or CH2; Y is CO or CH2; and n is 1 or 2) or a salt thereof has an excellent antiestrogenic activity, and is useful as a therapeutic agent of breast cancer, endometrial cancer, endometriosis, mastopathy, etc.

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