Novel benzoxazoles

Details Novel benzoxazoles Novel benzoxazoles

C - Chemistry, Metallurgy

07

D

C07D 263/56 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) C07D 263/57 (2006.01) C07D 277/64 (2006.01) C07D 413/02 (2006.01) C07D 413/06 (2006.01) C07D 413/12 (2006.01) C07D 417/02 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2202273

Novel compounds which are effective PDE IV inhibitors are disclosed. The compounds possess improved PDE IV inhibition as compared to theophylline or rolipram, with improved selectivity with regards to, e.g., PDE III inhibition.

L'invention concerne de nouveaux composés qui sont des inhibiteurs efficaces de la phosphodiestérase IV (PDE IV). Ces composés présentent une capacité améliorée d'inhibition de PDE IV par rapport à la théophylline ou au rolipram, ainsi qu'une sélectivité accrue par rapport notamment à l'inhibition de PDE III.

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