Novel benzylideneamino guanidines and their uses as ligands...

C - Chemistry – Metallurgy – 07 – C

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Details

C07C 281/18 (2006.01) A61K 31/155 (2006.01) A61P 29/00 (2006.01)

Patent

CA 2443057

The present invention relates to novel benzylideneamino guanidines of general formula and to the use of these benzylideneamino guanidines as melanocortin receptor agonists or antagonists. The invention further relates to benzylideneamino guanidines which show selectivity to the MC1 and MC4 melanocortin receptors as agonists and/or antagonists.

La présente invention concerne des benzylidèneamino guanidines représentées par la formule générale (I) suivante et leur utilisation en tant qu'agonistes ou antagonistes du récepteur de la mélanocortine. Cette invention concerne également des benzylidèneamino guanidines qui présentent une sélectivité à l'égard des récepteurs de la mélanocortine MC1 et MC4 en tant qu'agonistes et/ou antagonistes.

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