Novel .beta.-lactam antibiotics, methods for their...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 501/22 (2006.01) A61K 31/545 (2006.01) A61P 31/04 (2006.01) C07C 279/26 (2006.01) C07D 205/12 (2006.01) C07D 501/59 (2006.01) C08G 73/02 (2006.01) C12P 7/02 (2006.01) C12P 17/10 (2006.01) C12P 17/18 (2006.01) C12P 21/02 (2006.01) C07K 5/087 (2006.01)

Patent

CA 2677044

The invention relates to novel antimicrobial agents that are based on ß-lactam derivatives and are produced by reacting previously known ß-lactam derivatives with polyphenol oxidase substrates under the influence of free radicals and by forming salts of any ß-lactam derivatives with polyhexamethylene biguanide hydrogen carbonate. Said novel compounds are suitable as an antibiotic.

L'invention concerne de nouveaux principes actifs antimicrobiens à base de dérivés de ß-lactame. Ces nouveaux principes actifs sont produits, d'une part, par réaction de dérivés de ß-lactame connus avec des substrats de polyphénoloxydases sous l'influence de radicaux libres et, d'autre part, par salification de dérivés de ß-lactame quelconques avec de l'hydrogénocarbonate de polyhexaméthylène biguanide. Ces nouveaux composés conviennent comme antibiotiques.

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