C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 487/04 (2006.01) A61K 31/40 (2006.01) C07D 477/20 (2006.01)
Patent
CA 2264806
.beta.-Lactam compounds represented by general formula (1) and salts and esters thereof, wherein R1 represents a lower alkyl or an OH-substituted lower alkyl; R2 represents H or a lower alkyl; X represents O, S, or NH; n is 1 to 3; and R3 represents -C(Ra)=NH (wherein Ra represents H, a lower alkyl, or a substituted lower alkyl). The above compounds have an excellent antimicrobial activity against Gram-positive bacteria, particularly meticillin-resistant staphylococci and meticillin-resistant and coagulase-negative staphylococci.
L'invention concerne des composés du .beta.-lactame représentés par la formule générale (1), dans laquelle R?1¿ représente alkyle inférieur ou alkyle inférieur OH-substitué; R?2¿ représente H ou alkyle inférieur; X représente O, S ou NH; n est 1, 2 ou 3; et R?3¿ représente C(Ra)=NH (où Ra représente H, alkyle inférieur ou alkyle inférieur substitué); ainsi que leurs sels ou esters. Ces composés ont une excellente activité anti-microbienne contre les bactéries Gram positives, notamment les staphylocoques résistants à la méthicilline et les staphylocoques résistants à la méthicilline et coagulase-négatifs.
Nouda Hiroshi
Shinagawa Hisatoshi
Sunagawa Makoto
Yamaga Hiroshi
Kirby Eades Gale Baker
Nouda Hiroshi
Shinagawa Hisatoshi
Sumitomo Pharmaceuticals Company Limited
Sunagawa Makoto
LandOfFree
Novel .beta.-lactam compounds and process for preparing the... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel .beta.-lactam compounds and process for preparing the..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel .beta.-lactam compounds and process for preparing the... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1636742