C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 209/08 (2006.01) A61K 31/343 (2006.01) A61K 31/381 (2006.01) A61K 31/404 (2006.01) A61P 1/00 (2006.01) A61P 3/04 (2006.01) A61P 3/06 (2006.01) A61P 3/10 (2006.01) A61P 13/02 (2006.01) A61P 25/24 (2006.01) C07D 307/79 (2006.01) C07D 333/54 (2006.01)
Patent
CA 2407538
Compounds of the general formula (I): (see formula I) or a salt thereof, wherein R1 is hydrogen, hydroxyl or halogen; R2 is NHSO2CH3, SO2NHCH3 or the like; R5 and R6 each independently is hydrogen, C1-6 alkyl, optionally substituted phenyl or optionally substituted benzyl; X is NH, sulfur, oxygen or methylene; Y is oxygen, NR7, sulfur, methylene or a bond; and * represents an asymmetric carbon atom. The compounds are useful as a medicine for treating or preventing diabetes, obesity, hyperlipidemia, digestive diseases, depression or urinary disturbances.
La présente invention concerne des composés de formule générale (I) ou des sels de ces composés. Dans la formule (I): R<1> est hydrogène, hydroxyle, ou halogéno; R<2> est NHSO2CH3, SO2NHCH3, ou analogue; R<5> et R<6> sont indépendamment l'un de l'autre hydrogène, alkyle en C1-6, phényle éventuellement substitué, ou benzyle; X est NH, soufre, oxygène, ou méthylène; Y est oxygène, NR<7>, soufre, méthylène, ou une liaison; et * représente un atome de carbone asymétrique. Les composés de l'invention peuvent être utilisés comme substances de prévention et de traitement du diabète, de l'obésité, de l'hyperlipémie, des troubles digestifs, de la dépression, et des troubles urinaires.
Ikuta Shunichi
Miyoshi Shiro
Ogawa Kohei
Asahi Kasei Kabushiki Kaisha
Asahi Kasei Pharma Corporation
Goudreau Gage Dubuc
LandOfFree
Novel bicyclic compounds does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Novel bicyclic compounds, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Novel bicyclic compounds will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1767981